Author
University of California, Santa BarbaraORCID 0000-0003-1231-590XUnclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Jun W. Kim, SUSANNE R. MEYER, Ben Lopez…·Hyunsuk Min
The paper develops an anti-vitronectin antibody that reduces drusen accumulation and complement pathway activation in an in vitro model of age-related macular degeneration.
Dimitrios Pollalis, Gopa Kumar Gopinadhan Nair, Justin Leung…·Sun Young Lee
This study profiles miRNA in extracellular vesicles secreted during the maturation of human embryonic stem cell-derived RPE cells to inform EV-based therapeutics.
Orlando Chirikian, Mohamed A. Faynus, Markus W. Merk…·Beth L. Pruitt
This study shows that YAP overactivation in HCM mutant cardiomyocytes drives hypertrophy via CCN2 secretion and TGFβ uptake.
Dimitrios Pollalis, Constantin Georgescu, Jonathan D. Wren…·Sun Young Lee
This study investigates the therapeutic potential of RPE-secreted small extracellular vesicles in rescuing photoreceptors in retinal degeneration, showing gene expression reversal and functional improvement in a rat model.
Huishi Toh, Atefeh Bagheri, Colin N. Dewey…·Peng Jiang
The paper develops CRSP, a pipeline for RNA-seq analysis in species without a sequenced genome or reference transcripts, and applies it to generate a comprehensive Nile grass rat transcriptomic atlas.
Huishi Toh, Chentao Yang, Giulio Formenti…·Yury V. Bukhman
This paper presents a haplotype-resolved genome assembly of the Nile rat, revealing unique genomic features relevant to type 2 diabetes and metabolic dysfunctions.