Dao‐Fu Dai

CODAvision: best practices and a user-friendly interface for rapid, customizable segmentation of medical images

CODAvision provides a user-friendly interface for rapid, customizable medical image segmentation using deep learning, enabling non-experts to train and evaluate models across diverse imaging modalities.

Metabolic Reprogramming Induced by Mitochondrial Citrate Carrier Deletion Mitigates Antibiotics-Induced Acute Tubular Injury

This study shows that deleting the mitochondrial citrate carrier in kidney tubules reduces antibiotic-induced acute tubular injury by altering metabolism and increasing antioxidants.

The MICOS Complex Regulates Mitochondrial Structure and Oxidative Stress During Age-Dependent Structural Deficits in the Kidney

This study investigates age-related mitochondrial structural deficits in the kidney, finding that the MICOS complex is impaired, leading to increased oxidative stress and mitochondrial dysfunction.

Senescence and DNA Damage-Induced Inflammation Drive Heart Failure with Preserved Ejection Fraction in Cardiovascular Kidney Metabolic Syndrome

This study identifies DNA damage-driven senescence and ZBP1-cGAS-STING signaling as conserved mechanisms linking cardiovascular-kidney-metabolic comorbidities to HFpEF.

The mitochondrial regulation of smooth muscle cell proliferation in type 2 diabetes

This study investigates how mitochondrial dysfunction in T2D drives VSMC proliferation through Ca2+ regulation and Erk1/2 activation, showing that mtCaMKII inhibition reduces proliferation and neointima formation.