Author

Marthe Laisné

Centre National de la Recherche ScientifiqueORCID 0000-0003-1473-047XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Assay:DNA methylation· 1 Organism:human· 1

Frequent Co-Authors

Frédéric BonhommeiD· 2 shared Fumihito MiuraiD· 2 shared Kosuke YamaguchiiD· 2 shared Laure Ferry· 2 shared Olivier KirshiD· 2 shared Pierre‐Antoine DefosseziD· 2 shared Takashi ItoiD· 2 shared Adeline DurandiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersMolecular Biology

Frédéric BonhommeORCID

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintFeb 17, 2026

Matched single-cell chromatin, transcriptome, and surface marker profiling captures in vivo epigenomic reprogramming during basal-to-luminal transition in the mammary gland

Anna A. Karpukhina, Eve Moutaux, Adeline Durand…·Céline Vallot

The paper introduces OneCell CUT&Tag, a single-cell multi-omics method that captures chromatin, transcriptome, and surface marker data, revealing epigenomic reprogramming during mammary gland basal-to-luminal transition.

DOI 10.64898/2026.02.16.706078

mousescATAC-seq

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Molecular BiologyNature CommunicationsPeer-reviewedApr 5, 2024

Non-canonical functions of UHRF1 maintain DNA methylation homeostasis in cancer cells

Kosuke Yamaguchi, Xiaoying Chen, Brianna Rodgers…·Pierre‐Antoine Defossez

This study shows UHRF1 has non-canonical roles beyond DNMT1 activation in maintaining DNA methylation homeostasis in cancer cells.

57 citationstop 1%

humanDNA methylation

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Molecular BiologyNature Structural & Molecular BiologyPeer-reviewedJul 24, 2023

A genome-wide knock-out screen for actors of epigenetic silencing reveals new regulators of germline genes and 2-cell like cell state

Nikhil Gupta, Lounis Yakhou, Julien Richard Albert…·Pierre‐Antoine Defossez

The paper identifies new regulators of germline genes and 2-cell like cell state through a genome-wide CRISPR knock-out screen in mouse ES cells.

22 citations

mouseexperimental assay

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