Guohong Cui

Dopamine serves as an independent gain regulator to shape striatal control of movement

This study shows dopamine modulates striatal neuron activity to control movement by adjusting input-output efficacy in direct and indirect pathways.

A Hypothalamic Circuit that Modulates Feeding and Parenting Behaviors

This study identifies a hypothalamic circuit involving ARCAgRP and MPOABRS3 neurons that modulates the prioritization of feeding and parenting behaviors during lactation.

Monitoring norepinephrine release in vivo using next-generation GRABNE sensors

This paper develops improved GRABNE sensors to monitor norepinephrine release in vivo with high sensitivity and uses them to study NE dynamics in mice.

Spectral fiber-photometry derives hemoglobin concentration changes for accurate measurement of fluorescent sensor activity

This paper introduces spectral fiber-photometry methods to correct hemoglobin absorption artifacts in fluorescent sensor recordings, improving accuracy in measuring neuronal activity.

Chemogenetic Stimulation of Tonic Locus Coeruleus Activity Strengthens the Default Mode Network

This study shows that chemogenetic activation of locus coeruleus norepinephrine neurons strengthens functional connectivity in the default mode network in mice.

Deficiency in endocannabinoid synthase DAGLB contributes to Parkinson's disease and dopaminergic neuron dysfunction

This study shows that deficiency in DAGLB, an endocannabinoid synthase, contributes to Parkinson's disease by impairing dopaminergic neuron function and motor learning, with potential therapeutic implications for 2-AG augmentation.

New and improved GRAB fluorescent sensors for monitoring dopaminergic activity in vivo

The paper develops and optimizes GRABDA fluorescent sensors to monitor dopaminergic activity with high sensitivity and resolution in vivo.

A role for the locus coeruleus in the modulation of feeding

This study shows that locus coeruleus-norepinephrine (LC-NE) neurons modulate feeding by integrating external and internal cues, with their activity changing during food approach and consumption.

A genetically encoded fluorescent sensor for rapid and specific in vivo detection ofnorepinephrine

The paper develops GRABNE sensors for rapid, specific in vivo detection of norepinephrine, demonstrating their use in various experimental contexts.

A genetically-encoded fluorescent sensor enables rapid and specific detection of dopamine in flies, fish, and mice

This paper develops GRABDA sensors to measure dopamine with high precision in multiple organisms during complex behaviors.