Yerma Pareja Sanchez

The paper identifies mRNA stability regulation as a factor modulating transcriptional memory in yeast, showing it enhances gene expression remodelling in primed cells.

This study investigates on-target genomic effects of CRISPR/Cas9 deletions in human cells, revealing functional DNA disruptions and unexpected consequences.

This study shows that human prefoldin affects co-transcriptional pre-mRNA splicing by modulating RNA polymerase II phosphorylation and splicing factor recruitment.

The paper identifies chromatin-sensitive cryptic promoters in yeast that generate alternative protein isoforms through truncated mRNAs.