Author

Patrice Zeis

European Molecular Biology LaboratoryORCID 0000-0001-7615-2201Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Alexandar TzankoviD· 1 shared Alexandra GerberiD· 1 shared Alisa AlekseenkoiD· 1 shared Ana C. DelgadoiD· 1 shared Arquimedes ChefferiD· 1 shared Bingnan LiiD· 1 shared Bismark AppiahiD· 1 shared Camilla L. FullioiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperNeuroscience

Alexandar TzankovORCID

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3 papers

Recent·Most cited

The brain-meningeal interface functions as a reservoir and entry site for brain parenchymal macrophages

Deniz Kaymak, Phil T. Williams, Sabrina A. Hogan, Marie‐Françoise Ritz, Giulia Di Bartolomei, Sihan Zhu, Siling Du, Hassan Melhem, Ana C. Delgado, Tala Shekarian, Marta McDaid, Alexandra Gerber, Igor Smirnov, Patrice Zeis, Timo Schenker, , Gregor Hütter

The paper shows that CNS macrophage engraftment depends on TRM self-renewal and niche timing, not prolonged vacancy, and identifies a peripheral BAM-like macrophage population in aged human brains.

bioRxiv · Jul 20, 2026 · PreprintNeuroscience

Differential regulation of mRNA stability modulates transcriptional memory and facilitates environmental adaptation

Bingnan Li, Patrice Zeis, Yujie Zhang, Alisa Alekseenko, Eliška Fürst, Yerma Pareja Sanchez, Gen Lin, Manu M. Tekkedil, Ilaria Piazza, Lars Michael Steinmetz, Vicent Pelechano

The paper identifies mRNA stability regulation as a factor modulating transcriptional memory in yeast, showing it enhances gene expression remodelling in primed cells.

Nature Communications · Feb 17, 2023Peer-reviewedGenomics

DOT1L activity affects cell lineage progression in the developing brain by controlling metabolic programs

Bismark Appiah, Camilla L. Fullio, Christiane Haffner, Patrice Zeis, Martin Treppner, Patrick Piero Bovio, Arquimedes Cheffer, Ilaria Bertani, Harald Binder, Dominic Grün, Nereo Kalebic, Elena Taverna, Tanja Vogel

This study shows that DOT1L activity regulates AP lineage progression in the developing mouse neocortex by controlling metabolic programs and gene expression.

bioRxiv · Apr 8, 2022 · PreprintDevelopmental Biology