Author

Caitlin Davies

UK Dementia Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Neuroscience· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:cell-cell communication· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

Jane TullochiD· 4 shared Tara L. Spires‐JonesiD· 4 shared Colin SmithiD· 3 shared Jamie L. RoseiD· 3 shared Makis TziorasiD· 3 shared Anna J. StevensoniD· 2 shared Christopher M. HenstridgeiD· 2 shared Declan KingiD· 2 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersNeuroscience

Jane TullochORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer's disease

Martí Colom‐Cadena, Jamie Toombs, Elizabeth M. Simzer, Kristján Holt, Robert I. McGeachan, Jane Tulloch, Rosemary J. Jackson, James H. Catterson, Maxwell P Spires-Jones, Jamie L. Rose, Lora Waybright, Anthony O. Caggiano, Declan King, Francesco Gobbo, Caitlin Davies, , Tara L. Spires‐Jones

The paper identifies transmembrane protein 97 as a synaptic receptor for amyloid beta in human Alzheimer's disease using advanced microscopy and drug intervention studies.

Acta Neuropathologica · Feb 6, 2024Peer-reviewedNeuroscience

Human astrocytes and microglia show augmented ingestion of synapses in Alzheimer's disease via MFG-E8

Makis Tzioras, Michael J. D. Daniels, Caitlin Davies, Paul S. Baxter, Declan King, Sean McKay, Balazs Viktor Varga, Karla Popovic, Madison Hernandez, Anna J. Stevenson, Jack Barrington, Elizabeth Drinkwater, Julia Borella, Rebecca K. Holloway, Jane Tulloch, , Tara L. Spires‐Jones

The paper shows human astrocytes and microglia ingest more synapses in Alzheimer's disease via MFG-E8, and inhibiting MFG-E8 reduces this ingestion in cultured cells.

Cell Reports Medicine · Aug 30, 2023Peer-reviewedNeuroscience

Reducing voltage-dependent potassium channel Kv3.4 levels ameliorates synapse loss in a mouse model of Alzheimers disease

Jie Yeap, Chaitra Sathyaprakash, Jamie Toombs, Jane Tulloch, Cristina Scutariu, Jamie L. Rose, Karen Burr, Caitlin Davies, Martí Colom‐Cadena, Siddharthan Chandran, Charles H. Large, Matthew JM Rowan, Martin J. Gunthorpe, Tara L. Spires‐Jones

This study shows reducing Kv3.4 levels in a mouse model of Alzheimer's disease reduces synapse loss and changes in spine morphology.

Brain and Neuroscience Advances · Jan 1, 2022Peer-reviewedNeuroscience

Reducing tau ameliorates behavioural and transcriptional deficits in a novel model of Alzheimer’s disease

Eleanor K. Pickett, Abigail G. Herrmann, Jamie McQueen, Kimberly M. Abt, Owen Dando, Jane Tulloch, Pooja Jain, Sophie Louise Dunnett, Sadaf Sohrabi, Maria P. Fjeldstad, Will Calkin, Leo Murison, Rosemary J. Jackson, Makis Tzioras, Anna J. Stevenson, , Tara L. Spires‐Jones

This study shows that reducing tau improves behavioural and transcriptional issues in a mouse model of Alzheimer’s disease, suggesting synaptic tau reduction could be a therapeutic strategy.

bioRxiv · Aug 16, 2018 · PreprintNeuroscience