Connor C. Call

This paper introduces ORCA, a platform that uses oncogenic RNA sensing to target and ablate cancer cells, demonstrating efficacy in colorectal cancer models.

The paper introduces a single-cell screening platform called PIVOT for functional genetics in plants, demonstrating its ability to identify cytokinin signaling regulators.

The paper introduces LIDAR, a post-transcriptional synthetic receptor platform using RNA editing to sense ligands and produce functional outputs, enabling complex multicellular behavior programming.

This paper develops hDIRECT, a platform using human-derived proteins to control cytokine activity in cell-based therapies, demonstrating orthogonalization through protease regulation.

The paper develops a modular protein secretion platform with tunable logic and control for synthetic biology applications in cell therapies.