Matthew W. Kay

This study shows that TNFR2 agonism can prevent and reverse OA-induced cardiac dysfunction in female mice and delay systolic decline in males, revealing sex-specific cardiac effects of OA.

This study shows oxytocin improves survival and respiratory function in rats with opioid-induced respiratory depression caused by fentanyl or fentanyl-xylazine combinations, outperforming naloxone in some cases.

This study uses high-throughput pericellular oxygen measurements and computational modeling to assess how adrenergic drugs affect human iPSC-derived cardiomyocytes.

This study characterizes a novel mouse model of OA-induced heart failure, revealing sex-specific cardiac remodeling and molecular pathways associated with different HF phenotypes.

This study shows PDE1 regulates A2AR-associated cAMP signaling at the sarcolemma to enhance myocardial contractility in healthy and failing hearts.

This study identifies OXT receptor expression in brainstem cardiac vagal neurons and shows that OXT selectively activates DMNX CVNs to induce bradycardia.