Author

Tyler C. Cropley

New York UniversityORCID 0000-0003-2804-2555Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Beatrix M. UeberheideiD· 2 shared Adriana HeguyiD· 1 shared Alexander J. RuthenburgiD· 1 shared Amanda J. KeplingeriD· 1 shared Cynthia A. LoomisiD· 1 shared Daniele SimoneschiiD· 1 shared Drew Jones· 1 shared Ethan LaneiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

Beatrix M. UeberheideORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 18, 2026

Cyclin D-CDK4/6 couple proliferation to membrane and mitochondrial protein supply through a DeSI1 phospho-switch

Sharon Kaisari, Ethan Lane, Raymond Wang…·Michele Pagano

This study identifies DeSI1 as a cyclin D-CDK4/6 substrate whose phosphorylation regulates membrane and mitochondrial protein supply during proliferation.

DOI 10.64898/2026.09.16.752001

mouseproteomics

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Molecular BiologybioRxivPreprintMay 14, 2026

Bound for the nucleus: defining the molecular principles of cargo selection by importin 9

Amanda J. Keplinger, Tyler C. Cropley, Juliana Ortiz-Pacheco…·Beatrix M. Ueberheide

This study identifies 79 cargos bound by IPO9, showing it recognizes proteins without cNLSs, and defines structural elements that mediate cargo selection and release.

DOI 10.64898/2026.05.12.724649

proteomicsexperimental assay

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