Pol Andrés‐Benito

The paper identifies miR-519a-3p as a potential biomarker for preclinical stages of Alzheimer's disease by showing its early upregulation in AD cerebral samples.

The paper shows that tocilizumab, an IL-6 receptor inhibitor, prevents astrocyte-induced neurotoxicity in Parkinson's disease by blocking IL-6 signaling in neurons.

This study identifies a functional interaction between TDP-43 and USP10, showing USP10 modulates alternative splicing and can reduce TDP-43 toxicity in a mouse model of ALS and FTD.

This study investigates the role of cellular prion protein in tau seeding and spreading using Prnp mutant mice and P301S tauopathy models, finding it significant in the latter but not in Alzheimer's sarkosyl-derived samples.

The paper analyzes lipidomic changes in cerebral cortex and white matter of Alzheimer's disease patients, finding distinct lipid profiles associated with disease progression.

The paper identifies transcriptional signatures of synaptic vesicle genes associated with neurodegeneration in Myotonic Dystrophy Type I using transcriptome and brain imaging data.

This study identifies a differential lipidomic signature in nuclei of ALS patients, linking lipid changes to disease mechanisms.