Yu-Ying Chen

This study shows that intermittent heat exposure during mid-to-late gestation in mice leads to reduced anogenital distance and increased hypospadias in male embryos, without affecting gene expression in the fetal testis.

The paper demonstrates that using an empirically measured blank spectrum improves the accuracy of quantitative X-ray fluorescence mapping by reducing dependencies on dwell time and spectral aggregation.

The paper identifies Notch signaling as critical for specifying the interstitial lineage in fetal mouse ovaries through single-nucleus transcriptomics and lineage tracing.

This study shows that glycogen metabolism in Sertoli cells supports germ cell colonization during early testis development through lactate production, highlighting a critical metabolic dependency.

The paper identifies a transcriptional regulatory network in murine gonadal supporting cells that underlies sex differentiation, revealing how chromatin changes and gene expression drive Sertoli and granulosa cell fates.

This study uses single follicle RNA-seq to identify transcriptional signatures of ovarian follicles in mice, revealing stage-specific gene pathways involved in folliculogenesis.