Martin Andres Estermann

The paper uses PIP-seq to analyze gonadal cell transcriptomes in sea lamprey, identifying gene expression patterns associated with germ cell development and sexual differentiation.

This study shows that glycogen metabolism in Sertoli cells supports germ cell colonization during early testis development through lactate production, highlighting a critical metabolic dependency.

The paper identifies a transcriptional regulatory network in murine gonadal supporting cells that underlies sex differentiation, revealing how chromatin changes and gene expression drive Sertoli and granulosa cell fates.

The paper identifies Nr2f2 as a regulator of interstitial to fetal Leydig cell differentiation in mice, linking its dysfunction to disorders of sex development.

This paper develops a tamoxifen-inducible Cre mouse model, Nr2f2-iCreERT2, to specifically target interstitial cells in the reproductive system across developmental stages.

The paper shows that calcium signals at fertilization alter metabolic substrates, affecting epigenetic marks H3K27ac and H3K18la, which impact embryo development and offspring health.

This study uses single-nucleus multiomics to uncover gene regulatory networks and chromatin dynamics in murine PGCs during sex determination.

The paper identifies TOX3 as a transcription factor regulated by DMRT1 that modulates steroidogenic cell lineage expansion in chicken gonads.

The paper shows that fadrozole induces ovotestis in female chicken embryos by creating PAX2-positive undifferentiated supporting cells, while male embryos treated with estrogen lack these cells.

This study identifies TGIF1 as essential for chicken ovarian cortical and juxtacortical medulla development, independent of supporting cell sex lineage.