Author

Kovi R Shrung

Science for Life Laboratory

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:long-read sequencing· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Janne LehtiöiD· 2 shared Rui Mamede BrancaiD· 2 shared Alberto M. ArenasiD· 1 shared Alexandra Argyriou· 1 shared Ann-Charlotte BjörklundiD· 1 shared Anna Spinner· 1 shared Carmen Navarro Luzon· 1 shared Caroline KubaczkaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

Janne LehtiöORCID

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2 papers

Recent·Most cited

RNA splicing factor mutations drive myeloid neoplasm oncogenesis through protein complex poisoning

Pedro Luís Moura, Rui Mamede Branca, Yaroslav Kaminskiy, Ioannis Siavelis, Kovi R Shrung, Sophia Hofmann, Christina Maria Perraki, Alexandra Argyriou, Sadaf Fazeli, Masahiro M Nakagawa, Teresa Mortera Blanco, Steffen Boettcher, Caroline Kubaczka, Thorsten M. Schlaeger, Maria Creignou, , Eva Hellström-Lindberg

This study identifies how RNA splicing factor mutations drive myeloid neoplasm by disrupting proteomic networks through mis-splicing, validated via single-cell transcriptomics and proteomics.

bioRxiv · Sep 30, 2026 · PreprintCancer Biology

Pooled overexpression screening identifies PIPPI as a novel microprotein involved in the ER stress response

Lorenzo Lafranchi, Glancis L. Raja Arul, Alberto M. Arenas, Anna Spinner, Kovi R Shrung, Maximilian Hornisch, Dörte Schlesinger, Carmen Navarro Luzon, Linus Brinkenstråhle, Rui Shao, Ilaria Piazza, Janne Lehtiö, Rui Mamede Branca, Simon J. Elsässer

The paper uses pooled overexpression screens to identify PIPPI, a novel microprotein involved in the ER stress response, by screening sORFs for cytoprotective effects against 6-thioguanine.

Nucleic Acids Research · Oct 28, 2025Peer-reviewedCell Biology