Nadine Stokar‐Regenscheit

The paper investigates how ApoE4 affects intracellular trafficking and iron homeostasis in human brain endothelial cells derived from iPSCs, showing altered endosomal organization and iron levels.

This paper develops human lung alveolar immuno-organoids with autologous immune cells to model immune-epithelial interactions and study inflammation-related pulmonary side effects.

The paper uses single nuclei RNAseq to identify distinct glial gene expression patterns in MS patients, revealing subgroup-specific pathological processes and suggesting precision medicine approaches.

Paraffin histology, multiplex immunofluorescence and MALDI imaging work on blood-brain barrier organoids; an AI apoptosis detector on hematoxylin-eosin slides (F1 0.817 vs pathologists) tracked staurosporine dose responses.