Author

Abeer Heskol

Karolinska Institutet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Ana Mendanha FalcãoiD· 2 shared Diogo S. CastroiD· 2 shared Eneritz AgirreiD· 2 shared Gonçalo Castelo‐BrancoiD· 2 shared Mandy MeijeriD· 2 shared Alexandre A. S. F. RaposoiD· 1 shared Amit ZeiseliD· 1 shared Antonella ScaglioneiD· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersNeuroscience

Ana Mendanha FalcãoORCID

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Author profile →

4 papers

Recent·Most cited

Hierarchical reactivation of transcription during mitosis-to-G1 transition by Brn2 and Ascl1 in neural stem cells

Mário A. F. Soares, Diogo S. Soares, Vera Teixeira, Abeer Heskol, Raul Bardini Bressan, Steven M. Pollard, Raquel A. Oliveira, Diogo S. Castro

The paper shows that Brn2 and Ascl1 differentially bind mitotic chromosomes, influencing the timing of transcriptional reactivation during the mitosis-to-G1 transition.

bioRxiv · Feb 17, 2021Developmental Biology

A primed immune transcriptional program is activated in oligodendroglia in multiple sclerosis

Mandy Meijer, Eneritz Agirre, Mukund Kabbe, Cassandra A. van Tuijn, Abeer Heskol, Ana Mendanha Falcão, M. Ryan Corces, Thomas Jude Montine, Xingqi Chen, Howard Y. Chang, Gonçalo Castelo‐Branco

This study identifies a primed chromatin state in oligodendroglia that facilitates rapid activation of immune gene programs in multiple sclerosis.

bioRxiv · Jul 21, 2020 · PreprintNeuroscience

PADI2-mediated citrullination is required for efficient oligodendrocyte differentiation and myelination

Ana Mendanha Falcão, Mandy Meijer, Antonella Scaglione, Puneet Rinwa, Eneritz Agirre, Jialiang Liang, Sara Charlotte Buch-Larsen, Abeer Heskol, Rebecca Frawley, Michael Klingener, Manuel Varas‐Godoy, Alexandre A. S. F. Raposo, Patrik Ernfors, Diogo S. Castro, Michael Lund Nielsen, , Gonçalo Castelo‐Branco

This study shows that PADI2-mediated citrullination is essential for oligodendrocyte differentiation, myelination, and motor function, with implications for remyelination therapies.

Cell Reports · Apr 1, 2019Peer-reviewedNeuroscience

STRT-seq-2i: dual-index 5′ single cell and nucleus RNA-seq on an addressable microwell array

Hannah Hochgerner, Peter Lönnerberg, Rebecca D. Hodge, Jaromír Mikeš, Abeer Heskol, Hermann Hubschle, Philip Lin, Simone Picelli, Gioele La Manno, Michael Ratz, Jude Dunne, Syed Akhtar Husain, Ed S. Lein, Maithreyan Srinivasan, Amit Zeisel, Sten Linnarsson

The paper introduces STRT-seq-2i, a high-throughput single-cell RNA-seq platform, and demonstrates its application on fresh mouse and frozen human cortical samples.

Scientific Reports · Nov 21, 2017Peer-reviewedMolecular Biology