Peter M. Glazer

This study demonstrates systemic in utero gene editing using PNAs in nanoparticles to correct CFTR mutations in multiple organs of CF mice, showing sustained CFTR activity without off-target effects.

The paper identifies actin capping proteins as key modulators of therapeutic responses to radiation and immunotherapy through genome-scale CRISPR screens in melanoma cells.

This paper demonstrates that hydroxymethyl-γ PNA oligomers enhance gene modification in mouse bone marrow cells compared to diethylene glycol-γ PNA.

This study shows that activation of young LINE-1 elements in the cerebellum causes ataxia by inducing DNA damage, inflammation, and neuronal dysfunction in mice.