Stephen J. Crocker

Spoti-find is an open-source tool for analyzing void spot assays, introducing new metrics and improving usability and accuracy in urinary behavior studies.

This study identifies anastellin, a fibronectin-derived peptide produced by astrocytes lacking TIMP-1, which inhibits oligodendrocyte differentiation and reduces FTY720 efficacy in multiple sclerosis.

This study shows that CD8+ T-cell depletion prevents myelin pathology in a mouse model of Globoid Cell Leukodystrophy.

This study identifies synapse loss and microglial synaptic engulfment in MS models and demonstrates that targeted complement inhibition prevents synapse loss and visual dysfunction.

This study shows TIMP-1 reduces inflammatory pain through both MMP-dependent and receptor-mediated signaling mechanisms.