Author

Mélia Magnen

University of California, San FranciscoORCID 0000-0001-5189-0072Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Immunology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Mark R. LooneyiD· 3 shared Ari B. MolofskyiD· 1 shared Averil I. MaiD· 1 shared Bevin C. EnglishiD· 1 shared Catharina ConradiD· 1 shared Christian Ringler· 1 shared Clare L. AbramiD· 1 shared Clifford A. LowelliD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

Mark R. LooneyORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ImmunologyAmerican Journal of Respiratory Cell and Molecular BiologyPeer-reviewedFeb 6, 2026

Furin Inhibition Protects Against Acute Lung Injury in a Mouse Model of Pseudomonas Aeruginosa Infection

Olivier Bernard, Michael Kwon, Mark R. Looney…·Michelle A. Yu

This study shows that furin inhibition with BOS-318 reduces acute lung injury and improves survival in mouse models of Pseudomonas aeruginosa infection.

DOI 10.1093/ajrcmb/aanag024

mousebulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintOct 1, 2025

Fibroblast orchestration of inflammaging via NF-kB activation

Nancy C. Allen, Christian Ringler, Jin Young Lee…·Tien Peng

This study shows that aged fibroblasts activate NF-kB, leading to immune changes like exhausted T cells, autoimmunity, and cancer, increasing susceptibility to age-related diseases.

DOI 10.1101/2025.10.01.679697

mouseproteomics

𝕏 PostBluesky

ImmunologyJournal of Clinical InvestigationPeer-reviewedOct 1, 2024

Loss of neutrophil Shp1 produces hemorrhagic and lethal acute lung injury

Sayyed Farshid Moussavi-Harami, Simon J. Cleary, Mélia Magnen…·Mark R. Looney

This study shows that loss of neutrophil Shp1 causes severe lung injury and death in mice, and that activating Shp1 can reduce inflammation and lung damage.

22 citations

mousebulk RNA-seq

𝕏 PostBluesky