Jorgo Lika

The paper identifies sulfur-containing metabolites specific to inflammatory macrophages, showing they are produced from cysteine and central metabolism intermediates and are elevated in human inflammatory lesions.

Autofluorescence imaging informs manufacturing conditions that enhance yield and metabolic fitness of CAR T cells for neuroblastoma.

This study shows that mature neutrophils can rapidly reactivate mitochondrial metabolism in response to stimuli, impacting their function and suggesting therapeutic potential for mitochondrial pyruvate carrier inhibitors.