Author

James McCullagh

University of OxfordORCID 0000-0003-4733-1205Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

Akira WibergiD· 1 shared Anastasios ChanalarisiD· 1 shared Anthony TumberiD· 1 shared Christopher John SchofieldiD· 1 shared Christopher MarshalliD· 1 shared Clare E. MackayiD· 1 shared Clio DritsaiD· 1 shared Daniel M. WalliD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperMolecular Biology

Akira WibergORCID

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintNov 11, 2025

Inhibition of systemic mammalian metabolism by carnitine mimics from the gut microbiota

Katja Thümmler, Shyam Basak, Heather Hulme…·Daniel M. Wall

This study investigates the systemic effects of microbiome-derived carnitine analogues in mice, showing carnitine depletion and mitochondrial dysfunction due to inhibition of carnitine biosynthesis.

DOI 10.1101/2025.11.11.687811

mousemetabolomics

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NeurosciencebioRxivPreprintAug 9, 2023

Dopamine D2 receptor upregulation in dorsal striatum in the LRRK2-R1441C rat model of early Parkinson's disease revealed by in vivo PET imaging

Teresa Delgado‐Goñi, Natalie Connor‐Robson, Milena Cioroch…·Johannes Christian Klein

The paper uses PET imaging to show increased dopamine D2 receptor binding in LRRK2-R1441C rats, suggesting receptor upregulation as a compensatory response to dopamine deficits.

DOI 10.1101/2023.08.09.550512

ratimaging

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Molecular BiologyScience Translational MedicinePeer-reviewedDec 21, 2022

Variants in ALDH1A2 reveal an anti-inflammatory role for retinoic acid and a new class of disease-modifying drugs in osteoarthritis

Linyi Zhu, Pragash Kamalathevan, Lada A. Koneva…·Tonia L. Vincent

Analysis of hand OA cartilage stratified by ALDH1A2 polymorphic variants reveals a targetable, anti-inflammatory role for retinoic acid in OA.

47 citationstop 2%

humanbulk RNA-seq

𝕏 PostBluesky