BiophysicsbioRxivPreprint
A shear lag model of the podocyte foot process network predicts a mechanical feedback loop driving progressive effacement
Mingxuan Bi, Hanxun Jin, Pongpratch Puapatanakul…·Guy M. Genin
DOI 10.64898/2026.07.15.738799
Author
Pongpratch Puapatanakul
Washington University in St. LouisORCID 0000-0003-0633-5015Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2024-2026 · peak 3/yrCo-Author Collaboration Network
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Curved chords = mutual co-authorship5 papers
Recent·Most cited
- BiophysicsbioRxivPreprint
Synaptopodin enables directional mechanoadaptation of integrin-based adhesions
Chengqing Qu, Yuxuan Huang, Shumeng Jiang…·Hani Y. Suleiman
The paper shows synaptopodin enables cells to adapt their adhesion structures to resist perpendicular forces by reorganizing the actin cytoskeleton and integrin-based adhesions.
DOI 10.64898/2026.01.25.701551 - Cell BiologybioRxivPreprint
Orthogonal Force Balance Between Contractility and Shear Stress Governs Podocyte Dynamics
Shumeng Jiang, Pongpratch Puapatanakul, Chengqing Qu…·Hani Y. Suleiman
The paper identifies a mechanical homeostasis mechanism in podocytes where balance between fluid shear stress and cellular contractility prevents injury, showing that reducing blood pressure can worsen outcomes when contractility is impaired.
- Cell BiologybioRxivPreprint
Basement Membrane Structural Integrity Dictates Trans-Tissue Deposition of Laminin in Mammals
Kohei Omachi, Meei‐Hua Lin, Pongpratch Puapatanakul…·Jeffrey H. Miner
The paper shows that laminin-2 in the kidney glomerular basement membrane comes from circulating sources, not local cells, and that BM integrity affects this trans-tissue deposition.
DOI 10.1101/2025.04.28.650774 - Cell BiologyCytoskeletonPeer-reviewed
Ultrastructure expansion microscopy (U-ExM) of mouse and human kidneys for analysis of subcellular structures
Ewa Langner, Pongpratch Puapatanakul, Rachel Pudlowski…·Moe R. Mahjoub
This paper describes a U-ExM protocol for analyzing subcellular structures in mouse and human kidney tissues with high detail using conventional microscopy.