Matt Jones

Building Inclusive Leadership: A Biosciences Approach

The paper develops an Inclusive Leadership Programme for bioscientists to foster autonomy and inclusivity in research environments, showing it normalizes self-perception distributions and provides a baseline for best practices.

Systematic molecular glue drug discovery with a high-throughput effector protein remodeling platform

This paper introduces a platform for discovering molecular glue degraders by engineering effector proteins to enable systematic identification of new small molecule degraders targeting GSPT1.

Multiscale Light Field Microscopy Platform for Multi-purpose Dynamic Volumetric Bioimaging

This paper introduces a multiscale light field microscopy platform for fast 3D imaging across biological scales, demonstrating its use in whole-brain activity, calcium dynamics, and subcellular protein dynamics.

Assortative Mating Biases Marker-based Heritability Estimators

The paper shows that marker-based heritability estimators are biased under assortative mating and proposes corrected estimators for traits under equilibrium assortative mating.

Linkage disequilibrium between single nucleotide polymorphisms and hypermutable loci

The paper quantifies the correlation between SNPs and hypermutable loci across mutation rates, finding that high mutation rates reduce correlation while lower rates allow some tagging of hypermutable variation by SNPs.

A fast and accurate method for detection of IBD shared haplotypes in genome-wide SNP data

This paper introduces FISHR, a method for detecting IBD segments in SNP data, showing it is accurate for long segments and efficient for large datasets.