Author

Eden G. TenBarge

University of Tennessee at KnoxvilleORCID 0009-0001-6234-0807Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:flow cytometry· 1

Frequent Co-Authors

Andrew J. MonteithiD· 2 shared Agnieszka E. GorskaiD· 1 shared Anand Kamal SinghiD· 1 shared Anna SkwarskaiD· 1 shared Ashley D. WiseiD· 1 shared Bailey E. Holder· 1 shared Benjamin J. ReismaniD· 1 shared Brian O. BachmanniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Andrew J. MonteithORCID

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2 papers

Recent·Most cited

Specific F1 ATP synthase inhibition delivers transient mitochondrial stress for selective targeting of acute myeloid leukemia

Matthew T. Villaume, Haley Elizabeth Ramsey, Valeria Impedovo, Michael Davidson, Maria Pia Arrate, Anand Kamal Singh, Yujin Lee, Anna Skwarska, Yara. F. Almadani, Natalia Baran, Sovira Chaudhry, Benjamin J. Reisman, Eden G. TenBarge, Ming Jiang, Sarah D. Olmstead, , Michael Robert Savona

This study shows that inhibiting F1 ATP synthase with EB2023 causes transient mitochondrial stress in AML cells, enabling effective treatment without harming healthy tissues.

bioRxiv · Jul 13, 2026 · PreprintCancer Biology

A TLR7/9-IFNα-LDHB axis drives vital NET release and compromises antibacterial defense.

Eden G. TenBarge, Ashley D. Wise, Morgan Lynn Hetzel, Helene A Hoover, Helia Esfandiari, Bailey E. Holder, Eva Belevska, Ellie C Mennen, Sarah R McDaniel, Nicole M Vaccaro, Courtney C. Lucca, Jonathan M. Williams, Jennifer Ferris, Tim E. Sparer, Leslie J. Crofford, , Andrew J. Monteith

The paper identifies a TLR7/9-IFNα-LDHB axis that impairs NETosis in SLE, leading to bacterial susceptibility, and shows reversal with HCQ and IFNAR blockade.

bioRxiv · Oct 7, 2025 · PreprintImmunology