Author

Li Wan

University of PittsburghORCID 0009-0002-1858-9522Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Li Wan3 papers · Chinese Academy of Sciences

Biology Disciplines

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Immunology· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CRISPR screen· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Yuan ChangiD· 2 shared Bingxian XieiD· 1 shared Falguni PauliD· 1 shared Greg M. DelgoffeiD· 1 shared Howe CheniD· 1 shared Jeffrey Brodsky· 1 shared Joseph GonzaleziD· 1 shared Julia Hettleman· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersMolecular Biology

Yuan ChangORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintNov 9, 2026

A Human Tumor Virus Recruits HSP70 Chaperone to Remodel Its Replisome on DNA

Li Wan, Xiaochen Li, Paul Vittot…·Yuan Chang

This study shows that MCV small T protein recruits HSP70 to facilitate LT helicase remodeling and DNA unwinding, revealing a conserved mechanism for replication complex assembly.

DOI 10.64898/2026.11.05.764654

humanexperimental assay

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MicrobiologyScience AdvancesPeer-reviewedMay 8, 2026

The genetic landscape of antibiotic sensitivity in Staphylococcus aureus

Li Wan, Menghan Liu, Panos Oikonomou…·Wenyan Jiang

This study identifies gene-drug and gene-gene interactions in Staphylococcus aureus using CRISPR-interference, revealing vulnerabilities for new drug targets and combination therapies.

5 citationstop 1%

humanCRISPR screen

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ImmunologybioRxivPreprintOct 22, 2024

Engineered protein destabilization reverses intrinsic immune evasion for candidate vaccine pan-strain KSHV and SARS-CoV-2 antigens

Li Wan, Bingxian Xie, Masahiro Shuda…·Patrick S. Moore

The paper shows engineered destabilization of viral proteins enhances T cell recognition, improving vaccine efficacy against KSHV and SARS-CoV-2.

2 citations

mouseproteomics

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