Author

J Koch

University of Duisburg-EssenORCID 0009-0002-3344-7303Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Nina SchulzeiD· 3 shared Perihan NalbantiD· 2 shared Andrea VortkampiD· 1 shared Ann-Christine SevermanniD· 1 shared Annette PascheniD· 1 shared Barbara M. GrüneriD· 1 shared Bent BrachvogeliD· 1 shared Bikash AdhikariiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

Nina SchulzeORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Constitutive plasma membrane interaction of active Rho GEF Ect2 inhibits cortex contraction pulses

Kristina Mrug, Nina Schulze, Katarina Blažević, Konstantina Feller, J Koch, Leif Dehmelt, Perihan Nalbant

This study shows that constitutive plasma membrane association of active Ect2 suppresses pulsatile Rho activity dynamics during mitosis, unlike Lbc-type GEFs.

bioRxiv · Jun 6, 2026 · PreprintCell Biology

Targeted degradation of USP7 in solid cancer cells reveals disparate effects of deubiquitinase inhibition vs. acute protein depletion

Nikolas Klink, Sebastian Urban, Johanna A. Seier, Bikash Adhikari, Martin P. Schwalm, Juliane Müller, Madeleine Dorsch, Philine Steinbach, Jiwon Jung, Markus Vogt, Farnusch Kaschani, J Koch, Siska Führer, Markus Kaiser, Nina Schulze, , Malte Gersch

This paper compares the effects of USP7 inhibition and degradation in cancer cells, finding distinct phenotypic and proteomic responses.

Nature Communications · May 13, 2026Peer-reviewedBiochemistry

Heparan sulfate-function is essential for Integrin-dependent cell-matrix interactions and regulates glycosaminoglycan synthesis synthesis through YAP

Ann-Christine Severmann, Christoph Waterkamp, Meike Buchholz, Isabel Adorf, Lutz Fleischhauer, Julius Sefkow-Werner, Katja Jochmann, Tatjana Holzer, Velina Bachvarova, Nina Schulze, Johannes Koch, Bent Brachvogel, Elisa Migliorini, Hauke Clausen‐Schaumann, Perihan Nalbant, , Andrea Vortkamp

This study shows that heparan sulfate (HS) is critical for integrin-mediated cell-matrix interactions and regulates glycosaminoglycan (GAG) synthesis through YAP signaling in chondrocytes.

bioRxiv · Jan 8, 2026 · PreprintCell Biology