Fouad Choueiry

This study shows that a ketogenic diet prevents obesity-associated pancreatic cancer without weight loss but may promote cancer in non-obese models, altering specific metabolic pathways.

This study identifies purine nucleotides as molecular glues that regulate purine biosynthesis by tethering PPAT to NUDT5, and shows how thiopurine drugs function as metabolic glues with enhanced potency.

This study identifies Candida albicans colonization in colorectal tumors as a factor linked to reduced survival and impaired radiation response.

This study identifies silencing of ASS1 and upregulation of nucleotide biosynthesis as mechanisms of tamoxifen resistance in invasive lobular carcinoma.