Wuji Han

This study examines how different fixation methods affect SRS microscopy signals in HeLa cells, finding that Paraformaldehyde causes less disruption than other fixatives.

This paper introduces PRISM, a method for high-plex spatial RNA imaging using color intensity barcodes, validated across multiple tissues and showing the role of CAFs in tumor microenvironments.

The paper uses SRS microscopy to show caloric restriction extends C. elegans lifespan by inhibiting vitellogenesis, a process linked to protein buildup in the pseudocoelom.

The paper introduces SPRINTseq, a spatial transcriptomics method that enables fast, sensitive, and high-resolution data acquisition, revealing cellular and subcellular molecular architecture in Alzheimer's disease.