Pharmacology & ToxicologyNature CommunicationsPeer-reviewed
Targeting the Schwann Cell EP2/cAMP Nanodomain to Block Pain but not Inflammation
Romina Nassini, Lorenzo Landini, Matilde Marini…·Pierangelo Geppetti
The paper identifies a druggable EP2 receptor in Schwann cells that encodes PG-mediated persistent inflammatory pain without affecting protective inflammation.