Author

Carly Tyer

Oxford Nanopore Technologies (United Kingdom)ORCID 0009-0005-4205-7800Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:long-read sequencing· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Sissel JuuliD· 3 shared D. J. TurneriD· 2 shared Xiaoguang DaiiD· 2 shared Aditya S. DeshpandeiD· 1 shared Akash Sookdeo· 1 shared Alex W. DrongiD· 1 shared Benhur LeeiD· 1 shared Candy Haggblom· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersCell Biology

Sissel JuulORCID

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3 papers

Recent·Most cited

Cell BiologyNature CommunicationsPeer-reviewedJun 18, 2024

High resolution long-read telomere sequencing reveals dynamic mechanisms in aging and cancer

Tobias T. Schmidt, Carly Tyer, Preeyesh Rughani…·Jan Karlseder

This study introduces Telo-seq, a method using long-read sequencing to measure telomere lengths with high resolution, revealing dynamics in aging and cancer.

85 citationstop 1%

humanlong-read sequencing

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ImmunologybioRxivPreprintMar 26, 2024

De novo antibody discovery in human blood from full-length single B cell transcriptomics and matching haplotyped-resolved germline assemblies

John Beaulaurier, Lynn Ly, J. Andrew Duty…·Benhur Lee

This study uses single-cell transcriptomics and germline haplotype assembly to discover antibodies from human blood post-MMR vaccination, showing neutralization of measles virus.

3 citations

humanscRNA-seq

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GenomicsbioRxivPreprintNov 7, 2019

Nanopore sequencing of DNA concatemers reveals higher-order features of chromatin structure

Netha Ulahannan, Matthew Pendleton, Aditya S. Deshpande…·Marcin B. Imielinski

Pore-C reads multi-way chromatin contacts directly off unamplified Nanopore long reads, recovering Hi-C-scale features while also resolving rearranged cancer alleles and supporting de novo assembly.

51 citations

humanwhole-genome sequencing

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