Grigorios Panteloglou

The COPI coatomer influences LDL receptor activity, hepatic lipid storage, and apoB secretion

This study identifies COPI coatomer subunits that regulate LDL receptor activity, apoB secretion, and hepatic lipid storage, with genetic variants linked to elevated LDL-C levels.

Angiopoietin like protein 3 regulates low-density lipoprotein transport through aortic endothelial cells via endothelial lipase.

This study shows ANGPTL3 inhibits endothelial lipase-mediated LDL transport through aortic endothelial cells, which may explain mixed effects on ASCVD risk.

Dyslipidemic SPTLC3 Integrates Bile Acid-FXR Signaling with Sphingolipid Remodeling in MASLD

This study identifies SPTLC3's role in integrating bile acid-FXR signaling with sphingolipid remodeling in MASLD, showing its dysregulation in human liver and association with disease.