Xiaozhong Zheng

This study shows that proteostatic failure in ER-phagy, driven by Kras, leads to protein aggregates that prime acinar-ductal metaplasia and pancreatic cancer.

This study shows that blocking Kynurenine monooxygenase (KMO) reduces endometriosis-like lesions, alleviates pain, and improves behavior in a mouse model of endometriosis.

The paper identifies four distinct endotypes in acute pancreatitis using multiomic data and clinical metrics, showing diverse molecular and systemic responses.