Karel Stejskal

The paper identifies three urinary biomarkers for clear cell renal cell carcinoma using multi-omics analysis and develops a diagnostic score with 96% accuracy.

This study identifies SPARK as a conserved multi-protein complex essential for vertebrate fertilization, linking gamete recognition to membrane fusion.

This study compares the performance of Orbitrap Astral and Eclipse mass spectrometers in CLMS, finding the Astral provides higher sensitivity and more unique residue pairs.

The paper investigates the assembly and functional resilience of the RNA exosome in mouse embryonic stem cells using CRISPR/Cas9, revealing a hierarchical assembly pathway and quality control mechanisms.

This study harmonizes quality controls across proteomics core facilities to improve data comparability and reliability through a 4-year longitudinal dataset and common processing software.

The paper identifies a conserved trimeric complex of Izumo1, Spaca6, and Tmem81 essential for sperm-egg interaction in vertebrates, showing their role in male fertility and binding to the egg protein Bouncer.

This study shows that metabolic enzymes act as autophagy receptors in plants to degrade defense executors during viral infection, revealing autophagy as a tolerance pathway rather than an antiviral defense.