Cameron Genxuan Lian

This study identifies PSMε as a key molecular component that drives CD8+ T cell activation by commensal bacteria, offering a mechanism for immunotherapy without live bacterial colonization.

The paper shows that SMN inactivation causes CB components to invade the nucleolus, suppressing rRNA production and telomerase function through altered condensate interactions.

This paper identifies a PTP activity-independent mechanism by which SHP2 promotes RAS/ERK activation through direct binding to SOS1.