Author
Harvard UniversityORCID 0009-0007-7875-2682Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Guang‐Li Zhu, Shuhei Asada, Huy Q. Nguyen…·Alan D. D’Andrea
This study identifies a defect in MMEJ repair in SMARCB1-deficient tumors, leading to hyper-dependence on the FA/BRCA pathway, which can be targeted for therapy.
Feng Li, Amira Elbakry, Felix Y. Zhou…·Alan D. D’Andrea
This study identifies the CHAMP1 complex as a regulator of heterochromatin assembly and replication fork stability, showing its role in preventing genomic instability in cancer cells.
Guangli Zhu, Shuhei Asada, Jithma P. Abeykoon…·Alan D. D’Andrea
This study shows HPV16 E6 oncoprotein increases POLQ levels via UBE3A and RAD23A regulation, enhancing MMEJ to promote viral integration and oncogenesis.