Varahram Shahryari

This study identifies declining Wnt signaling as a driver of age-related alveolar stem cell loss and shows that restoring Wnt signaling in aged mice improves lung repair but not full regeneration.

This study shows that inhibiting PTPN1/2 enhances alveolar macrophage anti-metastatic activity through IFN-gamma-STAT1 signaling, offering a therapeutic strategy for metastasis.

This paper shows that an eIF2B activator rescues neonatal lethality in a VWM mouse model but leads to age-related motor deficits and myelin loss.