electrophysiology

OpenDrive provides an open-source microdrive system for high-density neurophysiology recording in large animals, enabling scalable and precise neuronal recordings.

The paper develops a high-throughput all-optical platform to map gene perturbations to electrophysiology using engineered hiPSCs and automated analysis.

This study shows that silent nociceptors are active during both phases of the formalin test in rats, suggesting their involvement in persistent pain mechanisms.

This study shows that advanced meditation stabilizes cortical dynamics through increased inhibitory gain and reduced temporal variability, linked to absorption depth.

This study examines how gaze patterns and EEG reflect the temporal dynamics of multi-item working memory maintenance, finding stable gaze encoding and no rhythmic alternation between items.

The paper quantifies electro-osmotic flow in MspA nanopores using a dipolar peptide and finite-element simulations, finding charged mutations near the constriction site enhance EOF.

The paper characterizes neural population heterogeneity during motor tasks using HF-LFPs and finds that heterogeneity varies by region and state, improving motor decoding.

The paper shows that glutamate and neuropeptide signaling in C. elegans males convert brief mate contact into a persistent search behavior.

This paper identifies EEG factors linked to FDG-PET dementia phenotypes, showing slowing and rhythm changes correlate with specific neurodegenerative subtypes.

This paper introduces local goodness-of-fit measures to assess state-space models in neural decoding, identifying when models poorly fit data during recordings.

This study shows that stimulating prefrontal beta oscillations at specific phases improves distinct cognitive functions: response inhibition at peak and working memory at trough.

This paper introduces DynISys, a model that infers neural dynamics and communication from multi-area recordings, revealing mechanisms for motor planning and execution.

This study compares the effects of AMPA receptor inhibitors on seizure-like events in murine and human brain slices, finding species-specific differences in drug efficacy.

This study shows that the EEG aperiodic exponent flattens with gastric fullness and correlates with vagal drive and gastric oscillations, suggesting it as a noninvasive biomarker for interoceptive attention.

This study shows that selective activation of estrogen receptors ER and ERβ modulates electrical activity and reduces basal insulin secretion in human EndoC-βH1 cells through extranuclear mechanisms.

This study links working memory capacity to directed exploration using behavioral, computational, and electrophysiological methods, showing that higher capacity is associated with better information use during exploration.

This paper develops a longitudinal BCI framework using neuronal avalanches and graph theory to predict future brain states during motor-imagery tasks, improving decoding accuracy and reducing calibration needs.

This study identifies three interacting brain networks involved in music recognition, showing how they dynamically coordinate sensory, memory, and decision processes.

This study investigates how distributional reinforcement learning is implemented in the basal ganglia by analyzing dopamine neuron activity and striatal representations.

This study shows maternal deprivation reduces adult-born granule cells in male mice, impairing social recognition, which can be reversed by enriched environments or abGC activation.

This study investigates whether pupil size reflects physical effort or motor fatigability during sustained repetitive movement and finds that it reflects effort but not fatigability.

This study investigates how ADHD affects exploration-exploitation trade-offs using a bandit task and EEG, finding heightened recent reward reliance and midfrontal sensitivity to outcome differences in ADHD without performance deficits.

The paper develops a computational model to simulate the self-assembly of cortical microcircuits from progenitors, reproducing experimentally measured connectivity without prescribing individual connections.

NeuroDisco provides optogenetic stimulation to neuronal cultures to reduce synchronized bursting and enable functional analysis of neuronal activity.

This study investigates the functional impact of the lurcher mutation in AMPA receptors, showing subunit-dependent effects on receptor kinetics and drug response.

This study uses wearable EEG and eye tracking to show that pupil-brain coupling has frequency-dependent organization and EEG-to-pupil directional coupling, comparable to stationary equipment.

This paper introduces hTSMNet, a method for zero-shot EEG decoding across datasets and paradigms using geometry-conditioned hyperalignment and Riemannian SPD manifold learning.

This study shows that tendon-specific PIEZO1 activation increases neural drive to muscle during high-load ballistic movements, without affecting muscle mass or myogenic gene expression.

This study identifies widespread oscillatory suppression in autism spectrum disorder across theta, alpha, and beta bands, confirmed in drug-naive patients.

This study investigates brain-body interactions during food anticipation using multimodal physiological recordings, finding distinct changes in gastric and cortical responses linked to appetite and craving.