Drosophila

This study identifies multiple Drosophila serpins with characteristics similar to human SERPINE1 using a multi-omics approach and comparative analysis.

The paper introduces mechanical reporters to decode the global mechanical landscape during Drosophila gastrulation by analyzing cephalic furrow dynamics.

The paper introduces PRISM to select low-fidelity simulators for multi-fidelity inference in vertex models, finding that early stopping is unreliable while coarser timesteps are effective.

This study identifies extensive horizontal gene transfer in the fungus gnat Bradysia coprophila, showing these genes contribute to stress tolerance and ecological adaptation.

The paper clusters filopodia dynamics using functional data analysis to identify distinct temporal patterns linked to Notch signaling in fruit fly development.

The paper investigates how gene expression influences genome-wide mutation rates in Drosophila melanogaster and Caenorhabditis elegans, finding that highly expressed genes have lower mutation rates due to transcription-coupled repair.

This study introduces SOPSim, a simulation tool that models sensory bristle patterning in fruit flies by incorporating filopodia dynamics and Notch signaling.

The paper identifies genes under co-evolutionary selection in Drosophila melanogaster by analyzing nucleotide diversity and divergence patterns, finding links to sperm competition and mating behaviors.

Earl Grey ParTEA annotates transposable elements across multiple genomes, revealing shared and private TE families and improving annotation consistency.

This study investigates how larval competition affects gene drive performance in Aedes aegypti mosquitoes using agent-based models and Bayesian optimization.

The paper shows that coarse-grained connectome partitions can preserve functional predictions about neural activity even when path structure is lost.

This study identifies genetic regulators of sugar-dependent food consumption in Drosophila using GWAS and RNAi knockdown.

The paper evaluates pesticide survival models by analyzing lesion persistence, showing that post-exposure death rates better reflect hazard structure than peak-based assumptions.

The paper shows that mutation transmission is influenced by developmental and life-history traits, altering mutation rates and identities across species.

This study identifies DPYD's role in sleep regulation through glial lipid metabolism and myelination across species, linking genetic variants to oligodendrocyte-specific control.

Path knockout identifies dominant multi-synaptic pathways in connectomes by quantifying the impact of neuron removal on connection strength, outperforming existing methods in Drosophila circuits.

This study identifies a conserved cold stress syndrome in insects, showing that hyperkalemia and ion homeostasis failure define chill tolerance across species and stress conditions.

The paper investigates how salinity affects algal growth, grazer survival, and interaction strength in a hypersaline system, finding that ecological responses to salinity are evolvable and influence the relationship between fundamental and realized niches.

This paper identifies genomic loci and mutations associated with DDT metabolic resistance in Anopheles gambiae using bulk segregant analysis and confirms their selection in natural populations.

This study examines how fructose-responsive gene regulation varies across intestinal regions in mice and fruit flies, finding conserved pathways and divergent metabolic responses.

This study shows that reducing neuroligin 3 in Drosophila extends lifespan and alters social behavior, linking synaptic function to longevity.

The paper evaluates methodological choices for analysing circadian activity data and identifies optimal approaches for different scenarios.

The paper examines microbial communities of invasive and native Drosophila species in French Guiana, identifying candidate taxa linked to host adaptation and competitiveness.

The paper demonstrates that a fixed neural wiring diagram in Drosophila can store and retrieve memories through neuronal adaptation, dependent on specific brain states.

The paper identifies de novo open reading frames in Drosophila melanogaster that show sequence signatures indicative of metal-binding potential through bis-histidine motifs.

The paper introduces Bvalcalc, a tool to calculate B-values, which quantify the effect of background selection on genetic diversity, and validates it using simulations and public data.

The paper identifies H3K36 methylation as critical for maintaining transcriptome fidelity in metazoans by suppressing aberrant initiation in heterochromatin.

This study uses intrinsic motivation algorithms to create agents that mimic Drosophila exploration behavior and neural representations of future actions.

This study tracks rapid wing size and shape changes in Drosophila sturtevanti across generations in lab conditions, showing genetic and environmental influences on morphology.

The paper uses a connectome model of the fruit-fly nervous system to simulate motor recovery after neuronal loss, finding that targeted cell replacement based on identity and connections improves recovery.