Marta Zlatic

Gain Control of Peripheral Input by Core Brain Thermosensors Drives Drosophila Thermoregulation

The paper identifies core brain thermosensors in Drosophila larvae that regulate thermoregulation by modulating the behavioral response to peripheral temperature inputs.

The female larval fly CNS connectome: first draft

The paper releases a complete larval Drosophila CNS connectome with automated segmentations and highlights the need for improved machine vision for proofreading.

Olfactory Loss Enhances Visual Learning in Drosophila through Structural and Functional Reorganisation

This study shows that losing olfaction in Drosophila enhances visual learning through structural and functional changes in neural circuits.

The central complex of the larval fruit fly brain

The paper identifies a putative larval central complex in Drosophila melanogaster, showing structural and connectivity similarities to the adult CX.

Descending neurons integrate learnt information from mushroom body with context to promote escape behaviour

The paper identifies a circuit mechanism in Drosophila larvae where descending neurons integrate learned information and contextual cues to activate specific escape behaviors.

A multisensory, bidirectional, valence encoder guides behavioral decisions

The paper identifies a neuron in Drosophila larvae that bi-directionally encodes valence and guides navigation based on sensory cues.

Beyond Agreement: Standardizing Crowdsourced Synapse Annotations through Proofreading in EM Connectomics

The paper introduces a standardized proofreading protocol for improving synapse annotations in EM connectomics by combining machine learning with multi-rater calibration and probabilistic modeling.

Combining brain-wide activity imaging with electron microscopy reveals a distributed brain network for processing threatening somatosensory stimuli

The paper combines brain-wide activity imaging with electron microscopy to identify a distributed neural network for processing threatening somatosensory stimuli in Drosophila larvae.

Cross-species comparative connectomics reveals the evolution of an olfactory circuit

This study uses cross-species connectomics to show that olfactory circuits have conserved core elements and species-specific rewiring linked to ecological differences.

A split-GAL4 driver line resource for Drosophila neuron types

The paper describes a collection of split-GAL4 driver lines for targeting specific neuron types in Drosophila, enabling functional and molecular studies.

Measuring the functional complexity of nanoscale connectomes: polarity matters

The paper develops a statistic called XORness to measure functional complexity in nanoscale connectomes and shows it is high in both real and generated connectomes with similar network statistics.

LarvaTagger: Manual and automatic tagging of Drosophila larval behaviour

LarvaTagger combines a pre-trained deep neural network with a GUI for manual tagging and training new automatic taggers using updated ground truth.

Statistical signature of subtle behavioural changes inlarge-scale behavioural assays

The paper introduces statistical methods to detect subtle behavioural changes in Drosophila larvae from large-scale behavioural assays.

The connectome of an insect brain

The paper maps the synaptic-resolution connectome of a Drosophila larva brain, identifying neuron types, circuit motifs, and structural features.

Serotonergic neurons mediate operant conditioning in Drosophila larvae

This study demonstrates operant conditioning in Drosophila larvae by optogenetically activating serotonergic neurons and shows the ventral nerve cord's role in memory formation.

Circuits for integrating learnt and innate valences in the fly brain

The paper maps convergence neurons in Drosophila that integrate innate and learned olfactory drives to mediate action selection.

Synaptic specificity is collectively determined by partner identity, location and activity

The paper investigates how synaptic connections in Drosophila are formed through partner-derived cues, global positional cues, and synaptic activity, showing that all three contribute to proper circuit assembly.

Mapping neurons and brain regions underlying sensorimotor decisions and sequences in Drosophila

The paper identifies neurons and brain regions in Drosophila larvae that influence sensorimotor decisions and sequence transitions in response to mechanosensory stimuli.

Comparative single-cell transcriptomics of complete insect nervous systems

The paper creates a comprehensive atlas of the Drosophila larval nervous system using single-cell transcriptomics and validates findings with RNA-FISH, revealing gene expression changes linked to behavioral states.

Multilevel feedback architecture for adaptive regulation of learning in the insect brain

The paper maps the synaptic connectome of the Drosophila larva mushroom body and identifies feedback pathways that enable modulatory neurons to compute teaching signals for reinforcement learning.

Neural substrates of navigational decision-making in Drosophila larva anemotaxis

This study identifies neuronal circuits in Drosophila larvae that mediate navigational decisions during anemotaxis, showing distinct modules control turning behavior in favorable and unfavorable conditions.

Organization Of The Drosophila Larval Visual Circuit

This paper maps the synaptic wiring diagram and neurotransmitters of the Drosophila larval visual circuit, revealing parallel circuits for light intensity and temporal changes.

The Complete Connectome Of A Learning And Memory Center In An Insect Brain

The paper reconstructs the complete synaptic connectome of the Drosophila larval mushroom body, revealing novel circuit structures and input integration patterns in Kenyon cells.