Neurobiology and Insect Physiology Research

The paper identifies a neuronal circuit in Drosophila that performs vector arithmetic to compute an allocentric traveling-direction signal.

This study identifies Otopetrin-Like A (OtopLA) as the acid taste receptor in Drosophila, showing its role in detecting protons and mediating acid avoidance behavior.

The paper links connectomic features to synaptic strengths and subcellular computations in Drosophila olfactory neurons.

This study identifies partially redundant functions of SLC5A transporters in Drosophila glial cells, affecting ovarian development and behavior.

This paper uses a computational model to show that non-synaptic interactions between olfactory receptor neurons in flies improve odor mixture detection and plume structure sensing but reduce dynamic range.

This paper shows that Drosophila grooming involves nested central pattern generators, with periodic behaviors at two time-scales that are linked and can decouple under different conditions.

The paper shows airflow creates a complex activation pattern in honeybee antennal lobes, combining mechanical and olfactory codes to encode airflow intensity, direction, and dynamics.

The paper shows that repeated odor exposure reduces ongoing activity variability and enhances odor representation specificity in fruit fly antennal lobe projection neurons.

This study identifies a three-part neural circuit in Drosophila that links satiety and fructose sensing to regulate feeding behavior.

This paper develops a technique for automated long-term two-photon imaging in head-fixed walking Drosophila over up to seven days.

The paper shows that compensatory variability in Kenyon cell parameters improves memory performance in Drosophila mushroom bodies by equalizing activity levels.

This study investigates how flight modulates heading representation in the monarch butterfly's central complex, revealing it functions as a global compass during flight.

The paper identifies a neural circuit in C. elegans that enables flexible control of persistent behavioral states through mutual inhibition between neuromodulatory systems and sensory input.

The paper examines the functional roles of co-receptors in Drosophila olfactory neurons by analyzing odor responses and gene expression changes in mutants.

The paper shows that the NLP-12 neuropeptide system in C. elegans modulates head and body motor circuits through CKR-1 and CKR-2 GPCRs to regulate food search behavior.

The paper maps convergence neurons in Drosophila that integrate innate and learned olfactory drives to mediate action selection.

This study identifies two pairs of Drosophila central brain neurons that negatively regulate light avoidance behavior by temperature through modulating downstream neural activity.

The paper provides a detailed structural analysis of the anterior sensilla in C. elegans dauer larvae using FIB-SEM, revealing previously unknown neuronal structures.

The paper shows how RIM interneurons in C. elegans use depolarized and hyperpolarized states to regulate motor behavior transitions through neurotransmitters and gap junctions.

The paper models the song recognition network in crickets to show how computational flexibility generates phenotypic diversity in pulse pattern recognition.

The paper shows that Drosophila beta-Heavy-Spectrin is essential for polarized ensheathing glia forming a diffusion barrier around the neuropil, affecting locomotion and brain compartmentalization.

The paper examines temporal dynamics of bitter taste responses in Drosophila, showing that bitter-sensing neurons exhibit both ON and OFF responses influencing synaptic plasticity and aversive learning.

This study examines how exercise affects climbing ability in Drosophila melanogaster, finding significant variation and sex- and genotype-dependent responses.

The paper presents the first complete connectome of the Drosophila central complex, revealing network motifs that support flexible navigation and context-dependent action selection.

The paper develops a GFP-based ELISA assay for rapid, quantitative genetic screens in Drosophila, identifying Syntaxins as novel regulators of astrocyte-mediated synapse elimination.

The paper investigates the evolution of olfactory receptor specificity in Drosophila by analyzing extant and ancestral IR receptors, identifying a common hotspot that influences ligand binding and functional transitions.

The paper measures state- and stimulus-dependent filtering properties of inputs to the Drosophila T5 cell and uses a connectomic-constrained model to reconcile motion computation with the circuit's anatomy.

This study identifies Nup54's role in Drosophila female reproductive behaviors by linking it to neuronal wiring and sexual differentiation in response to male sex-peptide.