Neurobiology and Insect Physiology Research

The paper shows that activated Ras/JNK signaling in Drosophila imaginal discs increases Dilp8 secretion, inhibits ecdysone synthesis, and causes early pupal death.

The paper shows that early-life starvation in C. elegans can permanently alter foraging behavior, associated with changes in a navigation circuit.

This study investigates the role of CREB1/CRH-1 isoforms in long-term memory and native behavior in C. elegans, identifying specific amino acids critical for memory formation.

The paper identifies modality-specific synaptic circuits in the fly's dorsal rim area that process linearly polarized skylight for orientation.

The paper shows that Tao kinase regulates synaptic growth and connectivity in Drosophila nociceptive circuits to maintain specificity and function during larval development.

The paper shows that hypoxia in Drosophila trh mutants causes glial-induced synaptic remodeling through HIF-1/Sima and Wg signaling, maintaining synaptic transmission for larval locomotion.

This study provides the first neuroanatomical atlas of Parhyale hawaiensis using immunohistochemistry and 3D reconstructions, revealing a brain structure with a modified lamina and elaborated central complex.

Flies compare an internal heading estimate with an internal goal angle to guide navigation.

The paper introduces STROBE, a closed-loop optogenetic system for controlling feeding behavior in Drosophila, showing it can drive attraction or avoidance based on sensory neuron activation.

This study investigates how olfactory and visual cues are integrated in mosquitoes, showing CO2 modulates visual responses and revealing asymmetrical, time-dependent neural coupling between these senses.

The paper shows that a neurotransmitter receptor in C. elegans is co-opted for inter-organismal communication via pheromone sensing.

This study identifies dCPD as a critical enzyme for neuropeptide processing in Drosophila, showing its role in behavior and survival.

The paper demonstrates a recurrent signaling loop between dopaminergic neurons and Kenyon cells in Drosophila larvae that mediates reward information and enhances memory persistence.

This study shows honey bees can use stimulus onset asynchrony to segregate unknown odorants from background odors, requiring a larger asynchrony than for known odors.

The paper demonstrates intrareceptor inhibition in mosquito odorant receptors through electrophysiological and behavioral studies.

This study identifies STIM-regulated neuropeptides, Corazonin and short Neuropeptide F, essential for Drosophila development under nutrient restriction.

The paper shows that maternal repression of NPF in Drosophila leads to transgenerational inheritance of ethanol preference through germline caspase activation.

The paper identifies DMon1 as a novel regulator in the brain-gonad axis, showing its role in female germline maturation through neuronal control of insulin production.

The paper shows that Weber-Fechner gain scaling in Drosophila ORNs improves odor identity coding under varying intensity and mixing conditions.

The paper develops FLLIT, a machine-learning tool for automated leg tracking in Drosophila, revealing distinct gait and tremor signatures in PD and SCA3 models.

The paper develops and validates optoPAD, a closed-loop optogenetics system to study how taste neurons influence feeding behavior in flies.

This study shows that mAChR-A in gamma Kenyon cells inhibits odor responses and is required for aversive olfactory learning in adult Drosophila.

This study shows that acetic acid elicits opposing feeding responses in Drosophila depending on hunger state, mediated by distinct taste pathways.

The paper uses live calcium imaging in Ae. aegypti larvae to study sensorimotor responses and foraging strategies, revealing the role of chemosensory systems.

The paper analyzes motor-related neural activity in larval Drosophila during fictive locomotion, identifying neurons biased toward forward or backward movement.

This study shows that C. elegans can transmit learned pathogenic avoidance behavior to multiple generations through epigenetic mechanisms, specifically involving the PRG-1/Piwi homolog.

This paper demonstrates that olfactory and neuromodulatory signals can reverse visual object avoidance to approach in Drosophila by modulating visual pathways.

This paper presents modular virtual flight arenas for studying skylight navigation in Drosophila, showing flies adjust headings in response to polarization changes.

The paper identifies 165 cell types in the Drosophila lateral horn and shows that 33 of them have stereotyped odor responses, revealing principles of odor categorization in a higher olfactory center.

This study identifies ppk301 as a critical ion channel for freshwater egg-laying in Aedes aegypti mosquitoes, showing its role in detecting water and salt concentrations.