Vestibular and auditory disorders

Evidence that ultrafast non-quantal transmission underlies short-latency vestibular evoked potentials.

The paper demonstrates that ultrafast non-quantal transmission underlies short-latency vestibular evoked potentials in guinea pigs.

Subchronic alteration of vestibular hair cells in mice: implications for multisensory gaze stabilization

This study investigates subchronic vestibular hair cell damage in mice, showing partial loss affects VOR and OKR, with reduced visuo-vestibular integration despite VOR recovery.

Nonquantal Transmission at the Vestibular Hair Cell-Calyx Synapse: KLV currents Modulate Fast Electrical and Slow K+ potentials in the Synaptic Cleft

The paper presents a computational model of nonquantal transmission at the vestibular hair cell-calyx synapse, showing how electrical potential in the synaptic cleft affects transmission latency and speed.

Enhancement of vestibular motion discrimination by small stochastic whole-body perturbations in young healthy humans

The paper shows that small stochastic whole-body perturbations improve vestibular motion discrimination thresholds in young healthy humans, suggesting a stochastic resonance mechanism.

Tilt In Place Microscopy (TIPM): a simple, low-cost solution to image neural responses to body rotations

The paper introduces Tilt In Place Microscopy (TIPM) to study neural responses to body rotations in larval zebrafish, showing reliable activity changes in vestibulospinal neurons during and after roll tilts.

The human brain networks mediating the vestibular sensation of self-motion

This study identifies brain networks involved in vestibular self-motion perception by analyzing rsfMRI data from TBI patients with and without vestibular agnosia.

Vestibular Compound Action Potentials and Macular Velocity Evoked by Sound and Vibration in the Guinea Pig.

This study investigates how transient sounds and vibrations activate vestibular afferents in guinea pigs by measuring mechanical and neural responses.

Observing the self and other in motion modulates the excitability of vestibulocollic reflexes

This study shows that observing human bodies in motion modulates vestibulocollic reflexes, with reduced VEMP amplitude when observing oneself compared to others.

The organization of the gravity-sensing system in zebrafish

The paper maps the zebrafish gravity-sensing system and shows that sensory tuning and developmental sequence organize vestibular topography.

Visuo-vestibular gaze control - conserved subcortical processing

This study uses an isolated lamprey preparation to show visuo-vestibular integration in subcortical circuits, revealing evolutionary conservation of gaze control mechanisms.

Simultaneous dual recordings from vestibular hair cells and their calyx afferents demonstrate multiple modes of transmission at these specialized endings

The paper examines multiple modes of transmission between vestibular hair cells and their calyx afferents using dual-electrode recordings, revealing distinct biophysical mechanisms.

Strategies of developmental vestibular plasticity after unilateral embryonic ear removal in Xenopus laevis

This study investigates how Xenopus laevis tadpoles develop gaze control mechanisms after unilateral embryonic ear removal, revealing compensatory strategies in vestibulo-ocular reflexes.

Distinct Representations of Body and Head motion are Dynamically Encoded by Purkinje cell Populations in the Macaque Cerebellum

The paper investigates how Purkinje cells in the macaque cerebellum encode body and head motion during self-motion, finding that most encode an intermediate representation combining vestibular and proprioceptive inputs.

Cortical facilitation of somatosensory inputs using gravity-related tactile information in patients with bilateral vestibular loss

The paper shows that patients with bilateral vestibular loss have heightened somatosensory cortex responses to plantar tactile inputs and use a tactile-based control strategy for balance.

Persistent horizontal and vertical, MR-induced nystagmus in resting state Human Connectome Project data

This study characterizes MR-induced nystagmus in resting state HCP data at 3T, finding persistent horizontal and vertical eye movements with no significant adaptation.

Mapping vestibular and visual contributions to angular head velocity tuning in the cortex

The paper maps the distribution of angular head velocity (AHV) sensitive neurons across cortical areas and identifies their dependence on vestibular and visual inputs.

Vestibular CCK neurons drive motion-induced malaise

The paper identifies CCK-expressing vestibular neurons as key drivers of motion-induced malaise and shows their role in inducing conditioned taste aversion through parabrachial nucleus activation.

Relationship between vestibular hair cell loss and deficits in two anti-gravity reflexes in the rat

This study examines how loss of vestibular hair cells in rats correlates with deficits in two anti-gravity reflexes, finding that type I hair cells are more sensitive to ototoxic damage than type II cells.

Stress Assessment of Vestibular Endurance Training for Civil Aviation Flight Students Based on EEG

The paper assesses stress responses during vestibular endurance training for flight students using EEG, finding that C3 and C4 brain regions show power changes correlated with anti-vertigo performance.

Synaptic Encoding of Vestibular Sensation Regulates Movement Timing and Coordination

This study investigates how vestibulospinal neurons in larval zebrafish encode body tilt and contribute to movement timing, coordination, and posture stability.

Two functionally distinct Purkinje cell populations implement an internal model within a single olivo-cerebellar loop

The paper shows two Purkinje cell populations in the cerebellum work together in a single olivo-cerebellar loop to implement an internal model of the otolith organs.

Robust vestibular self-motion signals in macaque posterior cingulate region

The paper identifies robust vestibular self-motion signals in macaque posterior cingulate cortex using motion stimuli and a 3D model, showing temporal components like velocity and acceleration.

L-Thyroxine improves vestibular compensation in a rat model of acute peripheral vestibulopathy

This study shows that L-Thyroxine treatment reduces vestibular syndrome and promotes compensation in a rat model of unilateral vestibular neurectomy.

Integration of vestibular and hindlimb inputs by vestibular nucleus neurons: Multisensory influences on postural control.

The paper investigates how vestibular nucleus neurons integrate vestibular and hindlimb proprioceptive inputs in conscious cats, finding that their activity during combined stimulation fits an additive model.

Central vestibular tuning arises from patterned convergence of otolith afferents

This study demonstrates that convergence of otolith afferents with similar or differing preferred directions shapes the tuning complexity of central vestibular neurons in zebrafish.

Selective Optogenetic Stimulation of Glutamatergic, but not GABAergic, Vestibular Nuclei Neurons Induces Immediate and Reversible Postural Imbalance in Mice

This paper uses optogenetics to show that glutamatergic vestibular nuclei neurons, but not GABAergic ones, cause immediate postural imbalance in mice.

Homeostatic cerebellar compensation of age-related changes of vestibulo-ocular reflex adaptation: a computational epidemiology study

This study models cerebellar mechanisms underlying age-related stability in VOR function, finding homeostatic plasticity compensates for structural declines.

Efferent Synaptic Transmission at the Vestibular Type II Hair Cell Synapse

This study investigates efferent synaptic inputs to type II vestibular hair cells using optogenetic and electrical stimulation, revealing hyperpolarization and facilitation during repetitive stimulation.

Comparisons among Vestibular Examinations and Symptoms of Vertigo in Sudden Sensorineural Hearing Loss Patients

The paper examines the relationship between vestibular function tests and hearing outcomes in sudden sensorineural hearing loss patients, finding associations between vertigo symptoms and disease severity.

Ancestral persistence of vestibulo-spinal reflexes in axial muscles in humans

This study investigates vestibulo-spinal reflexes in axial muscles, showing they persist in microgravity and during head contact, unlike limb muscles, suggesting a hard-wired reflex for posture control.