Nanoplatforms for cancer theranostics

Comparative Study of Photodynamic and Sonodynamic Therapy Using a PSMA-Targeted Up-conversion Nanoplatform for Castration-Resistant Prostate Cancer

This study compares NIR-PDT and SDT using a PSMA-targeted nanoplatform for castration-resistant prostate cancer, finding SDT provides superior therapeutic efficacy.

Direct Synthesis of Targeted Nanosized ICG J-aggregate for Photoacoustic Imaging

This paper develops a method to directly synthesize targeted nanoscale ICG J-aggregates for photoacoustic imaging, demonstrating their strong signal generation and functionalization potential.

Modular Albumin-Chaperoned NIR-II Nanofluorophores Enables Pan-Ovarian Cancer Imaging Across Multiscale Tumor Models

This paper develops NIR-II nanofluorophores for ovarian cancer imaging, showing improved brightness, stability, and targeting across multiple tumor models.

Croconium Dye Thermosensitive Liposomes for Light Activated Drug Release

This paper develops light-activated liposomes using croconium dye for on-demand drug release, showing tunable dexamethasone release and biocompatibility with HMEC-1 cells.

Simultaneous Cancer Treatment with Photothermal Therapy andChemotherapy using Gold nanorods coated with Methotrexate conjugatedHyaluronic acid

This paper develops a nanoplatform that combines photothermal therapy and chemotherapy using gold nanorods coated with methotrexate-conjugated hyaluronic acid, showing synergistic effects in vitro.

Next generation protein-corrole bio-assemblies provide effective tumoricidal treatment in a metastatic triple-negative breast cancer model

This paper develops a HER3-targeting protein-corrole nanocomplex that effectively treats metastatic triple-negative breast cancer with high tumor regression and survival improvement.

Biomimetic Cascade-Targeting Drug Delivery System for Reversing Chemoresistance in Osteosarcoma

This paper develops a drug delivery system to overcome chemoresistance in osteosarcoma by combining photothermal therapy and dual drug delivery with targeted nuclear release.

Copper Sulfide Nanoparticle-Mediated Photothermolysis Induces Immunogenic Cell Death in Ovarian Cancer Cells

The paper shows that CuS nanoparticle-mediated photothermolysis of ovarian cancer cells enhances dendritic cell activation and T cell expansion compared to ionizing radiation.

A Toolbox for the Personalization of Plasmonic Photothermal Therapy in Orthotopic Mouse Tumor Models

The paper develops a non-invasive toolbox to personalize plasmonic photothermal therapy in mouse tumor models by integrating optical and hemodynamic measurements with simulations.

Biomimetic Neoadjuvant Platform: Controlled Nanotoxicology as a Novel Approach to Preoperative Immunomodulation

This paper introduces a biomimetic nano-neoadjuvant platform that reprograms tumor microenvironments through immunomodulation, converting 'cold' tumors into immunogenic niches.

Supramolecular Biomimetic Topology: Macrophage-Engaged Neoadjuvant Platform for Preoperative Immunotherapy

This paper develops a nano-neoadjuvant platform using beta-glucan and carbon nanotubes to reprogram tumor microenvironments and enhance immunotherapy in advanced cancers.

Cellular Responses to Photothermal Therapy: Heat-Induced ERK Signaling and Intercellular Communication in Solid Tumors

This study examines how photothermal therapy affects ERK signaling and intercellular communication in tumor spheroids using FRET sensors and deep learning.

Tumor-targeted hydroxyapatite nanoparticles for dual-mode diagnostic imaging and near-infrared light-triggered photothermal cancer therapy

This paper develops tumor-targeted hydroxyapatite nanoparticles for dual-mode imaging and photothermal cancer therapy, showing effective tumor targeting and prolonged survival in vivo.

Hydrogen-bonded organic framework nanotransducers enabled sono-optogenetics for Parkinsonian rats

This paper develops a non-invasive optogenetics method using ultrasound-triggered nanotransducers to modulate Parkinsonian rats' neurons and improve movement dysfunction.

Biomimetic graphitic carbon nitride nanoparticles enable multiscale biomodulation

This paper introduces biomimetic graphitic carbon nitride nanoparticles that enable multiscale photo-modulation of cells and tissues through light-responsive mechanisms.