Cardiovascular Health and Disease Prevention

The Impact of Age and Sex on Cerebral and Large Artery Stiffness and the Response to Pulse Pressure

This study examines how age and sex affect cerebral and large artery stiffness and their response to pulse pressure in mice, finding that young females have more compliant arteries susceptible to endothelial dysfunction.

Biomechanical stress, inflammatory change and atheromatous plaque detachment: the role of pulse pressure, arterial wall stiffness and vessel bending. An in-vitro experimental study with some clinical implications

This study investigates the in vitro forces causing atheromatous plaque detachment, finding strong correlations between critical detachment force and pulse pressure, wall stiffness, and vessel bending.

Sex Differences in Middle Cerebral Artery Reactivity and Hemodynamics Independent from Changes in Systemic Arterial Stiffness in Adult Sprague-Dawley Rats

Pharmacological Activation of NO-Sensitive Guanylyl Cyclase Ameliorates Obesity-Induced Arterial Stiffness

This study shows that activating NO-sensitive guanylyl cyclase with cinaciguat reduces obesity-induced arterial stiffness by decreasing VSMC cytoskeletal actin polymerization.

The MAASWERP study: An international, comparative case study on measuring biomechanics of the aged murine aorta

The study compares two ex vivo setups for measuring aortic stiffness in aged mice, finding method-specific differences in stiffness parameters and smooth muscle cell effects.

Neurovascular Mechanisms of Cognitive Aging: Sex-Related Differences in the Average Progression of Arteriosclerosis, White Matter Atrophy, and Cognitive Decline

The paper investigates sex-related differences in the progression of arteriosclerosis, white matter atrophy, and cognitive decline using neuroimaging and behavioral data.

Sex moderates the relationship between aortic stiffness, cognition and cerebrovascular reactivity in healthy older adults

This study examines how sex and hematocrit influence the relationship between aortic stiffness, cerebrovascular reactivity, and cognitive function in older adults.

Carotid intima-media thickness in UK Biobank: Identification of novel genome-wide loci, sex-specific effects and genetic correlations with obesity and glucometabolic traits.

Genetic Association of Arterial Stiffness Index with Blood Pressure and Coronary Artery Disease

This study investigates whether genetic predisposition to higher arterial stiffness index (ASI) is associated with blood pressure and coronary artery disease risk, finding a link with blood pressure but not CAD.