Ferroptosis and cancer prognosis

Pan-cancer analysis reveals the value of FDX1 as a novel biomarker in the prognosis and immunotherapy in human tumors

This study identifies FDX1 as a prognostic biomarker and potential target for immunotherapy across multiple cancers using pan-cancer analysis.

DHCR7 as a novel regulator of ferroptosis in hepatocytes

This study identifies DHCR7 as a regulator of ferroptosis in hepatocytes, showing that its inhibition suppresses ferroptosis through 7-DHC accumulation and highlights its therapeutic potential for liver diseases.

A Novel Prognosis Model based on Comprehensive Analysis of Pyroptosis-Related Genes in Breast Cancer

The paper develops a prognostic model for breast cancer using pyroptosis-related genes, identifying 4 genes associated with overall survival and validating its effectiveness through multiple analyses.

Epigenetic regulation of translation repression in ferroptosis, and a role of Alternative splicing and tRNA methylation.

This study investigates how transcription and translation repression affect ferroptosis induced by different inhibitors, revealing distinct protective and detrimental effects based on the type of inducer.

Microglia ferroptosis is prevalent in neurodegenerative disease and regulated by SEC24B

The paper shows microglia are susceptible to ferroptosis in neurodegenerative diseases and identifies SEC24B and small molecules that regulate this process.

Identification of the Novel Pyroptosis-Related Gene Signature in Patients with Esophageal Adenocarcinoma

The paper identifies a five-gene pyroptosis-related signature associated with survival in esophageal adenocarcinoma patients using TCGA data.

Identification and verification of the potential effect of therapeutic miRNA-mRNA pairs on ferroptosis in small cell lung cancer by bioinformatics analysis

The paper identifies and verifies potential therapeutic miRNA-mRNA pairs affecting ferroptosis in SCLC using bioinformatics analysis and validation with additional data.