Author

Mindy Zhang

Sanofi (United States)ORCID 0000-0002-6038-2720Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1

Frequent Co-Authors

Dimitry OfengeimiD· 2 shared Jonathan D. ProtoiD· 2 shared Sean K. RyaniD· 2 shared Timothy R. HammondiD· 2 shared Anthony Chomyka· 1 shared Bailin ZhangiD· 1 shared Bruce D. TrappiD· 1 shared Cong LiiD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersNeuroscience

Dimitry OfengeimORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Microglia ferroptosis is prevalent in neurodegenerative disease and regulated by SEC24B

Sean K. Ryan, Matija Zelic, Yingnan Han, Erin A. Teeple, Luoman Chen, Mahdiar Sadeghi, Srinivas Shankara, Lilu Guo, Cong Li, Fabrizio Pontarelli, Elizabeth H. Jensen, Dinesh Kumar, Mindy Zhang, Joseph Gans, Bailin Zhang, , Timothy R. Hammond

The paper shows microglia are susceptible to ferroptosis in neurodegenerative diseases and identifies SEC24B and small molecules that regulate this process.

bioRxiv · Nov 2, 2021 · PreprintNeuroscience

Disrupted microglial iron homeostasis in progressive multiple sclerosis

Jonathan D. Proto, Mindy Zhang, Sean K. Ryan, Xinting Yao, Yinyin Huang, Yi-Chien Chang, Michael R. Dufault, Emilie Christie, Anthony Chomyka, Jackie Saleh, José Sancho, Timothy R. Hammond, Bruce D. Trapp, Dimitry Ofengeim

This study identifies SPMS-enriched microglia subsets with disrupted iron homeostasis and oxidative stress using snRNA-seq and validates findings with histology and RNA-scope.

bioRxiv · May 9, 2021 · PreprintNeuroscience