Topic · Molecular Biology · Biochemistry, Genetics and Molecular Biology
OpenAlex topic; a paper is listed when OpenAlex scores it at least 0.5 for this topic.
252 papers
Xin Li, Chong Chu, Jingwen Pei, Ion Măndoiu, Yufeng Wu
CircMarker detects circular RNA using k-mers instead of read mapping, achieving higher accuracy and efficiency than existing tools.
BMC Genomics · Aug 1, 2018Peer-reviewedBioinformatics
Xingjie-Bao, Xin-He, Shuying-Zheng, Yizhe-Luo, Tianlun-Gu, Ronghui-Tan, Jihan-Sun, Jinshun-Zhao, Lina-Zhang
The paper analyzes circRNA and miRNA expression profiles in essential hypertension using microarray and bioinformatics to identify potential circRNAs associated with the disease.
bioRxiv · Jul 25, 2018 · PreprintGenetics
Shobana Sekar, Lori Cuyugan, Jonathan R. Adkins, Philipp A. Geiger, Winnie S. Liang
The paper identifies circRNAs and their regulatory networks in posterior cingulate astrocytes from elderly subjects, finding enriched immune response pathways.
BMC Genomics · May 8, 2018Peer-reviewedNeuroscience
Nicholas K. Akers, Eric E. Schadt, Bojan Losic
STARChip detects circular RNA and fusion transcripts from chimeric alignments with high precision and speed, suitable for large-scale medical datasets.
Bioinformatics · Feb 16, 2018Peer-reviewedBioinformatics
Chong Tang, Tian Yu, Yeming Xie, Zhuqing Wang, Hayden McSwiggin, Ying Zhang, Huili Zheng, Wei Yan
The paper identifies artificial junction sequences formed by reverse transcriptases, leading to false circular RNA identification, and proposes methods to distinguish true circular RNAs.
bioRxiv · Feb 6, 2018 · PreprintMolecular Biology
Mariela Cortés-López, Matthew Gruner, Daphne A. Cooper, Hannah N. Gruner, Alexandru-Ioan Voda, Alexander M. van der Linden, Pedro Miura
This study identifies age-related accumulation of circRNAs in C. elegans and links it to postmitotic cell composition and circRNA stability.
BMC Genomics · Jan 3, 2018Peer-reviewedGenomics
AFCMEasyModel is a user-friendly Shiny app for simulating competing endogenous RNA networks using ODEs, allowing parameter modification and visualization of sponge complex formation.
bioRxiv · Dec 31, 2017 · PreprintBioinformatics
Steven P. Barrett, Kevin R. Parker, Caroline Horn, Miguel A. Mata, Julia Salzman
The paper identifies the promoter of ciRS-7 as overlapping with LINC00632 and shows ciRS-7 exonic sequence is embedded in linear transcripts in human and mouse.
PLoS Genetics · Dec 13, 2017Peer-reviewedGenetics
Vanessa Chong-Morrison, Tatjana Sauka‐Spengler
The paper identifies a novel class of circular RNAs in zebrafish embryonic cells that arise from tandem duplicated genes and are enriched on polysomes.
bioRxiv · Nov 15, 2017 · PreprintMolecular Biology
Ammar Zaghlool, Adam Ameur, Chenglin Wu, Jakub Orzechowski Westholm, Adnan Niazi, Manimozhi Manivannan, Kelli S. Bramlett, Mats F. Nilsson, Lars Feuk
This study develops methods to detect, quantify, and visualize circRNAs in human tissues and shows their potential as diagnostic biomarkers in blood and serum.
bioRxiv · Aug 31, 2017 · PreprintGenomics
Bin Li, Xiaoqin Zhang, Shurong Liu, Shun Liu, Wenju Sun, Qiao Lin, Yu-Xia Luo, Keren Zhou, Chen-Min Zhang, Ye-Ya Tan, Jianhua Yang, Liang‐Hu Qu
The paper introduces circScan, a method to identify circRNA-RBP interactions from CLIP-seq data, finding thousands of novel interactions in human and mouse genomes.
bioRxiv · Mar 11, 2017 · PreprintMolecular Biology
Lu Chen, Pei Zhang, Yuan Fan, Juan Huang, Qiong Lu, Qing Li, Jianbing Yan, Gary J. Muehlbauer, Patrick S. Schnable, Mingqiu Dai, Lin Li
The paper identifies circRNAs in maize formed by transposon reverse complementary pairs and links them to phenotypic variation through expression changes and gene interactions.
bioRxiv · Jan 15, 2017 · PreprintGenomics