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This paper introduces a streamlined LC-MS assay for quantifying peptide degradation in cell culture without sample purification, enabling efficient assessment of peptide stability and functionality.

This study demonstrates that low-pressure isochoric freezing can inhibit microbial growth and preserve food quality for up to 5 weeks using raw cow's milk as a model.

This study develops a microfluidic system to control intracellular pH dynamics and validates a mathematical tool to translate fluorescence signals to pH values, revealing overshooting and undershooting pH responses.

This study develops and validates a fully animal component-free media for adherent mammalian cell lines, showing comparable morphology, growth, and transcriptomic profiles to FBS-based media.

This paper introduces CDRxAbs, a new class of antibody-small-molecule conjugates designed to enhance target binding affinity and specificity through computational protein design.

This study uses reinforcement learning to simulate age-related balance strategy shifts in sarcopenia by training agents on a musculoskeletal model.

This paper shows that enantiomeric histidine-rich peptides form coacervates that enhance antigen delivery to T cells, improving immune response.

This paper introduces a human mesofluidic intestinal chip to study transport of drug carriers and bacteria through a live mucosal barrier, revealing mucus dynamics and particle interactions.

This study investigates how microfluidic flow parameters affect solute transport in 3D cell cultures, showing that chamber size, inlet velocity, and confinement influence solute distribution and penetration depth.

This study evaluates the feasibility of continuous head turn monitoring using wearable sensors, finding high reliability and establishing normative data in healthy adults.

This study shows that pancreatic ductal adenocarcinoma cells in collagen droplets form branched organoids with complex morphology, suggesting accelerated maturation compared to traditional bulk culture.

This paper develops a high-performance brain-computer interface for finger control and quadcopter navigation, achieving fast target acquisition and obstacle course performance.

This study develops tunable porcine skin-derived hydrogels for 3D bioprinting, optimizing their mechanical properties and printability to support cellular growth and structure formation.

This study investigates how dynamic hydrogel crosslink strength affects yielding behavior and cell viability during injection, finding that slower yielding transitions enhance cell protection.

This paper develops orally deliverable milk-derived nanovesicles loaded with Cx43 peptides to treat cardiac ischemia-reperfusion injury, showing >60% reduction in infarct size in mice.

This paper introduces a microfluidic rheometer to measure tumor spheroid mechanics and invasiveness in a physiologically relevant setting, finding that tumor stiffness and viscoelastic properties correlate with invasiveness.

This paper develops a thiol-ene click chemistry strategy to modify HPMC for tunable PNP hydrogel properties, enabling controlled drug and cell delivery.

This paper investigates the biocompatibility of residual human hair with varying keratin-associated protein (KAP) levels, finding that lower KAP levels reduce foreign body response in vivo.

This study examines how muscle co-contraction affects sit-to-stand performance in women wearing high-heeled shoes, finding that increased co-contraction leads to compensatory strategies that may cause imbalance and fatigue.

This study investigates how dense DNA packing on polymeric nanoparticles enhances duplex stability and hybridization specificity for nucleic acid sensing.