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The paper introduces BLOC, a modular organ-on-a-chip system that allows flexible configuration for diverse applications in MPS research.

This study improves cellulase activity through protein supercharging, identifying a variant with 2-3-fold higher activity on cellulosic substrates and demonstrating its synergistic potential with endocellulases.

The paper develops and validates new methods for ECM decellularization and collagen purification that preserve structural and biochemical integrity, applicable to various cell types for tissue engineering and drug discovery.

This study develops a WSAO-OCT platform to visualize retinal cells in live mice, showing improved image quality and detecting RGC degeneration after optic nerve injury.

Regularized single-cell imaging in nanowells enables training of generalizable AI models for accurate, stain-free viability screening across previously unseen cell types and contexts.

The paper develops a multi-parametric imaging system to study cAMP, transmembrane potential, and calcium in the heart, showing cAMP activation correlates with electrophysiological responses.

This study introduces a scalable organoid model of urothelial aging to investigate metabolic changes and test interventions for age-related bladder dysfunction.

This paper estimates spatial image gradients from diffusion MRI signals by modeling relaxation-time properties, showing significant correlation with gold-standard gradients across multiple datasets.

This study evaluates how hypoxia affects lipid nanoparticle-mediated mRNA delivery to placental cells and shows that therapeutic mRNA can restore protein levels under hypoxic conditions.

This paper develops a low-cost methyl cellulose-based ethanol gel for topical treatment of low-grade cervical dysplasia, showing efficacy in vitro and stability under various storage conditions.

This paper develops a biohybrid scaffold using functionalized silk fibroin to enhance charge-transfer efficiency, promoting neurite outgrowth in dorsal root ganglion neurons under electrical stimulation.

This paper introduces engineered magneto-sensitive fluorescent proteins that enable quantum sensing in living cells through optically detected magnetic resonance.

This study develops synthetic mucin-based hydrogels for localized delivery of anti-TNF- antibodies in IBD, showing improved retention and reduced systemic exposure.

This study examines how substituents on benzyl groups affect self-assembly and immunogenicity of amphipathic peptides, showing that chemical modifications influence fibril formation and immune responses.

This study shows that targeting DNA-LNPs to endothelial cells enhances transgene expression magnitude, duration, and specificity in target organs.

The paper develops a high-pressure reactor to monitor methanogenic microbial growth under deep saline aquifer conditions and finds increased methane production with higher H2/CO2 partial pressures.

This study compares the transcriptomic profiles of LPS-induced immune responses in homeRNA and venous blood samples, showing homeRNA captures comparable inflammatory responses.

This paper introduces an acoustofluidic device to improve microtissue histology by pre-patterning microtissues in HistoGel, simplifying downstream processing and increasing efficiency.

This study uses stem cells to deliver magnetic nanoflowers for targeted photothermal therapy, improving tumor retention and enabling MPI-guided ablation with no recurrence.

The paper describes a modular method to create targeted gas vesicle protein nanoparticles using His-tagged antibody fragments and Ni-NTA functionalization, validated for PSMA targeting.