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This study shows how climbing plants use self-generated motion and mechanical properties to detect and respond to environmental supports.

This study investigates how substituting the azadithiolate ligand in ToHydA affects O2-stability by preventing the formation of specific states and altering structural dynamics.

This paper investigates how whirligig beetles generate hydrodynamic torque for rapid surface-to-underwater diving by bending their abdomen.

This paper derives a metabolic cost-based model for optimal vascular tree shear stress profiles and shows how staged growth and fluctuating demand influence vascular topology.

The paper introduces Zephyr, a diffusion model for generating structural ensembles of disordered proteins, achieving high accuracy and faster sampling than molecular dynamics simulations.

The paper tests a dynamical model of PU.1 regulation during hematopoietic differentiation and finds that additional regulatory inputs beyond autoregulation and C/EBP feedback are required to explain observed data.

This study uses molecular dynamics simulations to investigate conformational changes in the ND2 subunit of complex I, revealing a previously unobserved structural transition linked to proton pumping.

This paper introduces a method using ultrasonic excitation in plunge freezing tweezers to reduce preferred particle orientation in cryo-EM, achieving a complete reconstruction of hemagglutinin at 2.5 Å resolution.

This study identifies a 'kiss-and-ride' mechanism for lipid transfer mediated by Osh6, showing that transient membrane tethering facilitates cargo extraction and transport.

This study investigates the functional roles of red chlorophylls in the PSI core antenna by mutating specific sites and analyzing structural and spectroscopic changes.

This study shows that Gag proteolysis drives HIV-1 Env conformational closure through the gp41 cytoplasmic tail, revealing a mechanism for immune evasion.

This study maps 5mC and H3K9me3 co-localization on individual chromosomes using AFM, revealing mechanical stiffness differences between cancer and non-tumorigenic cells.

The paper studies how mechanical forces, bacterial growth, and viral infection dynamics interact during the expansion of an E. coli colony, revealing phage hitchhiking and anisotropic spread.

This study identifies CTL1 as a phospholipid-binding protein that deforms membranes, revealing its structural basis and potential role in phospholipid homeostasis.

The paper identifies an anisotropic attractor and predictive feedback control mechanism governing cellular density homeostasis using single-cell mass-volume measurements.

This paper introduces fp-SMD to simulate single-molecule force spectroscopy data by aligning simulation timescales with experiments, revealing force-induced pathway switching in a host-guest complex.

The paper derives a non-equilibrium model for biomolecular condensate sorting, identifying a critical Damkohler number threshold for bistability and quality control.

This study uses experimental and molecular dynamics methods to show that Aβ40 and Aβ42 have distinct co-assembly pathways with lipids, with lipid effects varying by isoform and lipid composition.

This paper introduces a method to adjust tmFRET distance sensitivity using different metal ions at a single bpyA-labeled protein site, enabling conformational change measurements.

This study shows that ionic strength and ionization affect membrane-tethered polymer conformation, which influences membrane curvature generation through changes in brush thickness and grafting density.